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Conoidin A

Product Specifications

CAS Number

18080-67-6

Target

Parasite

Related Pathways

Microbiology/Virology

Purity

0.9877

Bioactivity

Conoidin A is a cell-permeable inhibitor of the T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 ?M. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for research on ischaemic heart disease.

Smiles

[O-][n+]1c(CBr)c(CBr)[n+]([O-])c2ccccc12

Molecular Formula

C10H8Br2N2O2

Molecular Weight

347.99

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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