Conoidin A
Product Specifications
CAS Number
18080-67-6
Target
Parasite
Related Pathways
Microbiology/Virology
Purity
0.9877
Bioactivity
Conoidin A is a cell-permeable inhibitor of the T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 ?M. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII) . Conoidin A has antioxidant, neuroprotective effects and can be used for research on ischaemic heart disease.
Smiles
[O-][n+]1c(CBr)c(CBr)[n+]([O-])c2ccccc12
Molecular Formula
C10H8Br2N2O2
Molecular Weight
347.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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