3MB-PP1
Product Specifications
CAS Number
956025-83-5
Target
CDK, DAPK, PLK
Related Pathways
Cell Cycle/Checkpoint, Apoptosis
Purity
0.9997
Bioactivity
3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor. In cells expressing analog-sensitive Plk1 alleles, 3MB-PP1 blocks mitotic progression and cell division arise by targeting Plk1. 3MB-PP1 specifically inhibits analog-sensitive Ssn3 (Cdk8) . 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase with IC50 of 2 μM. 3MB-PP1 can be used for the research of cell division and hypha formation of Candida albicans.
Smiles
Cc1cccc(Cc2nn(c3ncnc(N)c23)C(C)(C)C)c1
Molecular Formula
C17H21N5
Molecular Weight
295.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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