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MG-115

Product Specifications

CAS Number

133407-86-0

Target

Proteasome, Apoptosis

Related Pathways

Apoptosis, Ubiquitination, Proteases/Proteasome

Purity

0.9712

Bioactivity

MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis [1] [2] [3].

Smiles

CCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C=O

Molecular Formula

C25H39N3O5

Molecular Weight

461.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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