MG-115
Product Specifications
CAS Number
133407-86-0
Target
Proteasome|||Apoptosis
Related Pathways
Apoptosis|||Ubiquitination|||Proteases/Proteasome
Purity
0.9712
Bioactivity
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteasome, induces p53-dependent apoptosis [1] [2] [3].
Smiles
CCCC(NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C=O
Molecular Formula
C25H39N3O5
Molecular Weight
461.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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