AAL-993
Product Specifications
CAS Number
269390-77-4
Target
VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9965
Bioactivity
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.
Smiles
FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1
Molecular Formula
C20H16F3N3O
Molecular Weight
371.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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