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AAL-993

Product Specifications

CAS Number

269390-77-4

Target

VEGFR

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9965

Bioactivity

AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.

Smiles

FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1

Molecular Formula

C20H16F3N3O

Molecular Weight

371.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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