NSC 66811

Product Specifications

CAS Number

6964-62-1

Target

Mdm2, MDM-2/p53

Related Pathways

Apoptosis

Purity

0.9694

Bioactivity

NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2) -p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.

Smiles

Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1

Molecular Formula

C23H20N2O

Molecular Weight

340.42

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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