NSC 66811
Product Specifications
CAS Number
6964-62-1
Target
Mdm2, MDM-2/p53
Related Pathways
Apoptosis
Purity
0.9694
Bioactivity
NSC 66811is a novel inhibitor of the murine double minute 2 (MDM2) -p53 interaction. It binds to MDM2 with a Ki of 120 nM and activates p53 in cancer cells with a mechanism of action consistent with targeting the MDM2-p53 interaction.
Smiles
Cc1ccc2ccc(C(Nc3ccccc3)c3ccccc3)c(O)c2n1
Molecular Formula
C23H20N2O
Molecular Weight
340.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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