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HBX 41108

Product Specifications

CAS Number

924296-39-9

Target

Apoptosis, MDM-2/p53, DUB, p53

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination, Apoptosis

Purity

0.9965

Bioactivity

HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.

Smiles

Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N

Molecular Formula

C13H3ClN4O

Molecular Weight

266.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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