HBX 41108
Product Specifications
CAS Number
924296-39-9
Target
Apoptosis, MDM-2/p53, DUB, p53
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Ubiquitination, Apoptosis
Purity
0.9965
Bioactivity
HBX 41108 (HBX-41108) is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBX 41108 inhibited deubiquitination of p53 mediated by USP7 in a dose-dependent manner with an IC50 of 0.8μM.
Smiles
Clc1ccc-2c(c1)C(=O)c1nc(C#N)c(nc-21)C#N
Molecular Formula
C13H3ClN4O
Molecular Weight
266.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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