(E/Z) -Zotiraciclib
Product Specifications
CAS Number
937270-47-8
Target
JAK, FLT, CDK
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells
Purity
0.9992
Bioactivity
(E/Z) -Zotiraciclib ((E/Z) -TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively.
Smiles
CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2
Molecular Formula
C23H24N4O
Molecular Weight
372.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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