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(E/Z) -Zotiraciclib

Product Specifications

CAS Number

937270-47-8

Target

JAK, FLT, CDK

Related Pathways

Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells

Purity

0.9992

Bioactivity

(E/Z) -Zotiraciclib ((E/Z) -TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively.

Smiles

CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2

Molecular Formula

C23H24N4O

Molecular Weight

372.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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