(E/Z) -Zotiraciclib

937270-47-8

JAK, FLT, CDK

Chromatin/Epigenetic, Cell Cycle/Checkpoint, JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells

0.9992

(E/Z) -Zotiraciclib ((E/Z) -TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively.

CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2

C23H24N4O

372.46

Ice Packs

-20°C