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Phleomycin

Product Specifications

CAS Number

11006-33-0

Target

Antibiotic, Antibacterial, DNA/RNA Synthesis

Related Pathways

Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair

Bioactivity

Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.

Smiles

NC1=NC(C(NCC(N)C(N)=O)CC(N)=N)=NC(C(NC(C(O[C@@]2(OC3[C@H](O)[C@@](O)(C(N)=O)[C@@H](O)C(CO)O3)[C@H](C)[C@@H](O)[C@H](O)[C@H](CO)O2)C4=CNC=N4)C(C(O)C(C)C(NC(C(C)=O)C(NCCC5=NC(C6=NC(C(N)=O)=CS6)CS5)=O)=O)=O)=O)=C1

Molecular Formula

C48H69N17O20S2

Molecular Weight

1268.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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