Aloisine A
Product Specifications
CAS Number
496864-16-5
Target
Others, ERK, GSK-3, JNK, CDK, CFTR
Related Pathways
Stem Cells, Cell Cycle/Checkpoint, MAPK, Membrane transporter/Ion channel, PI3K/Akt/mTOR signaling, Others
Bioactivity
Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM) .
Smiles
C(CCC)C1=C(NC=2C1=NC=CN2)C3=CC=C(O)C=C3
Molecular Formula
C16H17N3O
Molecular Weight
267.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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