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JNJ-28312141

Product Specifications

CAS Number

885692-52-4

Target

Others, c-Fms

Related Pathways

Tyrosine Kinase/Adaptors, Others

Bioactivity

JNJ-28312141 is an orally active CSF1R inhibitor and a FLT3 inhibitor. JNJ-28312141 is a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.

Smiles

N(C(=O)C=1NC(C#N)=CN1)C2=C(C=C(C=C2)C3CCN(C(CN(C)C)=O)CC3)C=4CCCCC4

Molecular Formula

C26H32N6O2

Molecular Weight

460.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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