Picoplatin
Product Specifications
CAS Number
181630-15-9
Target
Others, DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Others, Cell Cycle/Checkpoint
Bioactivity
Picoplatin has a broad spectrum of antineoplastic activity and is designed to overcome platinum drug resistance. Picoplatin alkylates DNA, forming both intra- and inter-strand cross-linkages, resulting in the inhibition of DNA replication and transcription, and the induction of apoptosis.
Smiles
[Pt+2]([Cl-])([Cl-])([NH3])[N]=1C(C)=CC=CC1
Molecular Formula
C6H10Cl2N2Pt
Molecular Weight
376.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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