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MK-0731

Product Specifications

CAS Number

845256-65-7

Target

Others|||Apoptosis|||Kinesin|||Lipoxygenase

Related Pathways

Cytoskeletal Signaling|||Metabolism|||Apoptosis|||Others

Bioactivity

MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase and apoptosis in tumor cells that overexpress KSP.

Smiles

C(O)[C@@]1(N(C(N(C)[C@@H]2[C@H](F)CN(C)CC2)=O)CC(=C1)C3=C(F)C=CC(F)=C3)C4=CC=CC=C4

Molecular Formula

C25H28F3N3O2

Molecular Weight

459.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/D74E1C7E-41B7-419D-818E-D463A015F45B/T21321

Available Sizes

Curated Selection

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