MK-0731
Product Specifications
CAS Number
845256-65-7
Target
Others|||Apoptosis|||Kinesin|||Lipoxygenase
Related Pathways
Cytoskeletal Signaling|||Metabolism|||Apoptosis|||Others
Bioactivity
MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase and apoptosis in tumor cells that overexpress KSP.
Smiles
C(O)[C@@]1(N(C(N(C)[C@@H]2[C@H](F)CN(C)CC2)=O)CC(=C1)C3=C(F)C=CC(F)=C3)C4=CC=CC=C4
Molecular Formula
C25H28F3N3O2
Molecular Weight
459.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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