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Veliparib dihydrochloride

Product Specifications

CAS Number

912445-05-7

Target

PARP, Autophagy

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy

Purity

0.9981

Bioactivity

Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.

Smiles

Cl.Cl.C[C@@]1(CCCN1)c1nc2c(cccc2[nH]1)C(N)=O

Molecular Formula

C13H18Cl2N4O

Molecular Weight

317.21

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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