Veliparib dihydrochloride
Product Specifications
CAS Number
912445-05-7
Target
PARP, Autophagy
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy
Purity
0.9981
Bioactivity
Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.
Smiles
Cl.Cl.C[C@@]1(CCCN1)c1nc2c(cccc2[nH]1)C(N)=O
Molecular Formula
C13H18Cl2N4O
Molecular Weight
317.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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