Navitoclax
Product Specifications
CAS Number
923564-51-6
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
>99.99%
Bioactivity
Navitoclax (ABT-263) is a potent oral Bcl-2 inhibitor that binds to Bcl-xL, Bcl-2, and Bcl-w proteins (Ki<1 nM), demonstrating antitumor activity and inducing apoptosis.
Smiles
C(C1=C(CCC(C)(C)C1)C2=CC=C(Cl)C=C2)N3CCN(CC3)C4=CC=C(C(NS(=O)(=O)C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN6CCOCC6)CSC7=CC=CC=C7)C=C5)=O)C=C4
Molecular Formula
C47H55ClF3N5O6S3
Molecular Weight
974.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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