Navitoclax

Product Specifications

CAS Number

923564-51-6

Target

Bcl-2 Family

Related Pathways

Apoptosis

Purity

>99.99%

Bioactivity

Navitoclax (ABT-263) is a potent oral Bcl-2 inhibitor that binds to Bcl-xL, Bcl-2, and Bcl-w proteins (Ki<1 nM), demonstrating antitumor activity and inducing apoptosis.

Smiles

C(C1=C(CCC(C)(C)C1)C2=CC=C(Cl)C=C2)N3CCN(CC3)C4=CC=C(C(NS(=O)(=O)C5=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN6CCOCC6)CSC7=CC=CC=C7)C=C5)=O)C=C4

Molecular Formula

C47H55ClF3N5O6S3

Molecular Weight

974.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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