CX-5461
Product Specifications
CAS Number
1138549-36-6
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.994
Bioactivity
CX5461 is an rRNA synthesis inhibitor with oral activity that inhibits Pol I-driven rRNA transcription. CX5461 activates the DNA damage response and has antitumor activity in tumors such as ovarian cancer.
Smiles
CN1CCCN(CC1)c1ccc2c(n1)n1c3ccccc3sc1c(C(=O)NCc1cnc(C)cn1)c2=O
Molecular Formula
C27H27N7O2S
Molecular Weight
513.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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