Seliciclib
Product Specifications
CAS Number
186692-46-6
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E (IC50=0.1 μM) . Seliciclib also inhibits Cdk7/cyclin H, Cdk5/p35 and Cdc2/cyclin B (IC50=0.49/0.16/0.65 μM) . Seliciclib has antitumor activity.
Smiles
CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1
Molecular Formula
C19H26N6O
Molecular Weight
354.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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