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Fimepinostat

Product Specifications

CAS Number

1339928-25-4

Target

PI3K|||Apoptosis|||HDAC

Related Pathways

PI3K/Akt/mTOR signaling|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic

Purity

0.9987

Bioactivity

Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types.

Smiles

COc1ccc(cn1)-c1nc(N2CCOCC2)c2sc(CN(C)c3ncc(cn3)C(=O)NO)cc2n1

Molecular Formula

C23H24N8O4S

Molecular Weight

508.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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