Adavosertib
Product Specifications
CAS Number
955365-80-7
Target
Wee1
Related Pathways
Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
Adavosertib (MK-1775) is a small molecule inhibitor of the checkpoint kinase WEE1 (IC50: 5.2 nM) . It hinders the G2 DNA damage checkpoint.
Smiles
C(C=C)N1N(C=2C(C1=O)=CN=C(NC3=CC=C(C=C3)N4CCN(C)CC4)N2)C=5N=C(C(C)(C)O)C=CC5
Molecular Formula
C27H32N8O2
Molecular Weight
500.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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