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Quizartinib

Product Specifications

CAS Number

950769-58-1

Target

Ligands for Target Protein for PROTAC, Autophagy, FLT, Apoptosis

Related Pathways

Autophagy, Apoptosis, PROTAC, Angiogenesis, Tyrosine Kinase/Adaptors

Purity

0.9942

Bioactivity

Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.

Smiles

CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCN4CCOCC4)ccc32)no1

Molecular Formula

C29H32N6O4S

Molecular Weight

560.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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