Teprenone

Teprenone is an anti-ulcer agent, and works as an inducer of heat shock proteins (HSPs) .

Product Specifications

CAS Number

[6809-52-5]

Product Name Alternative

Geranylgeranylacetone

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

HSP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Teprenone.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O

Molecular Formula

C23H38O

Molecular Weight

330.55

Precautions

H302, H315, H319, H335

References & Citations

[1]Hirakawa T, et al. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology. 1996 Aug;111 (2) :345-57.|[2]Caprioli J, et al. Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model. Trans Am Ophthalmol Soc. 2003;101:39-50; discussion 50-1.|[3]Han NK, et al. Geranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction. Int J Mol Sci. 2017 Oct 7;18 (10) .