Teprenone
Teprenone is an anti-ulcer agent, and works as an inducer of heat shock proteins (HSPs) .
Product Specifications
CAS Number
6809-52-5
Product Name Alternative
Geranylgeranylacetone
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Teprenone.html
Purity
99.58
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O
Molecular Formula
C23H38O
Molecular Weight
330.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Hirakawa T, et al. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology. 1996 Aug;111 (2) :345-57.|[2]Caprioli J, et al. Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model. Trans Am Ophthalmol Soc. 2003;101:39-50; discussion 50-1.|[3]Han NK, et al. Geranylgeranylacetone Ameliorates Intestinal Radiation Toxicity by Preventing Endothelial Cell Dysfunction. Int J Mol Sci. 2017 Oct 7;18 (10) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
HSP
Available Sizes
Frequently Asked Questions
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