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NNK

Product Specifications

Target

Lipoxygenase

Related Pathways

Metabolism

Purity

>99.99%

Bioactivity

NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKC? signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.

Smiles

CN(CCCC(=O)c1cccnc1)N=O

Molecular Formula

C10H13N3O2

Molecular Weight

207.23

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/439B1270-1352-46E3-BFC8-538B98BAB815/T20533

CAS Number

64091-91-4

Available Sizes

Curated Selection

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