Macropa-NH2 (hydrochloride)
Product Specifications
UNSPSC Description
Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/macropa-nh2-hydrochloride.html
Purity
99.51
Solubility
DMSO : 83.33 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Smiles
O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1.[H]Cl
Molecular Weight
584.06
References & Citations
[1]Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.J Nucl Med. 2021 Aug 12;jnumed.121.262459.|Patent. US20210236667A1.|Sci Rep. 2020 Dec 17;10(1):22203.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111895A/Macropa-NH2-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111895A/Macropa-NH2-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2443966-86-5
Available Sizes
Curated Selection
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