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Macropa-NH2 (hydrochloride)

Product Specifications

UNSPSC Description

Macropa-NH2 hydrochloride is the precursor of Macropa-NCS. Macropa-NCS is conjugated to Anti-Human HER2 (HY-P9907) as well as to the prostate-specific membrane antigen-targeting compound RPS-070 and is a promising therapeutic radionuclide applied in the treatment of soft-tissue metastases[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/macropa-nh2-hydrochloride.html

Purity

99.51

Solubility

DMSO : 83.33 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL

Smiles

O=C(O)C1=NC(CN2CCOCCOCCN(CC3=NC(C(O)=O)=CC=C3)CCOCCOCC2)=CC(N)=C1.[H]Cl

Molecular Weight

584.06

References & Citations

[1]Thiele NA, et al. An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717.J Nucl Med. 2021 Aug 12;jnumed.121.262459.|Patent. US20210236667A1.|Sci Rep. 2020 Dec 17;10(1):22203.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-111895A/Macropa-NH2-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-111895A/Macropa-NH2-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2443966-86-5

Available Sizes

Curated Selection

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