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MLN9708 analogues

Product Specifications

CAS Number

1201902-80-8

Target

Proteasome, Autophagy

Related Pathways

Autophagy, Proteases/Proteasome, Ubiquitination

Purity

0.9923

Bioactivity

MLN2238 suppresses the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (Ki50=0.93 nM, IC50=3.4 nM/) . The biologically active form of MLN9708 (Ixazomib Citrate) is MLN2238 in aqueous solutions or plasma.

Smiles

CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)CC(CC(O)=O)(O1)C(O)=O

Molecular Formula

C20H23BCl2N2O9

Molecular Weight

517.12

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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