LY294002
Product Specifications
CAS Number
154447-36-6
Target
Autophagy|||Apoptosis|||Casein Kinase|||DNA-PK|||PI3K
Related Pathways
Stem Cells|||PI3K/Akt/mTOR signaling|||Apoptosis|||Autophagy|||Metabolism|||DNA Damage/DNA Repair
Purity
0.9996
Bioactivity
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3K?, PI3K?, and PI3K? (IC50=0.5/0.57/0.97 ?M) . LY294002 is also an inhibitor of DNA-PK (IC50=1.4 ?M) and an inhibitor of CK2 (IC50=98 nM) . LY294002 activates apoptosis and autophagy.
Smiles
O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1
Molecular Formula
C19H17NO3
Molecular Weight
307.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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