Fedratinib
Product Specifications
CAS Number
936091-26-8
Target
JAK, FLT, Apoptosis, c-RET
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Angiogenesis, Chromatin/Epigenetic, Apoptosis
Purity
0.9996
Bioactivity
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
Smiles
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C
Molecular Formula
C27H36N6O3S
Molecular Weight
524.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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