Fedratinib
Product Specifications
CAS Number
936091-26-8
Target
JAK|||FLT|||Apoptosis|||c-RET
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Apoptosis
Purity
0.9996
Bioactivity
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
Smiles
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C
Molecular Formula
C27H36N6O3S
Molecular Weight
524.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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Histone H2B Type 1-C/E/F/G/I (Histone H2B.1 A, Histone H2B.a, H2B/a, Histone H2B.g, H2B/g, Histone H2B.h, H2B/h, Histone H2B.k, H2B/k, Histone H2B.l, H2B/l, HIST1H2BC, H2BFL, HIST1H2BE, H2BFH, HIST1H2BF, H2BFG, HIST1H2BG, H2BFA, HIST1H2BI, H2BFK)
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