Mertansine
Product Specifications
CAS Number
139504-50-0
Target
ADC Cytotoxin, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Antibody-drug Conjugate/ADC Related
Purity
>99.99%
Bioactivity
Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.
Smiles
CO[C@@H]1\C=C/C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2
Molecular Formula
C35H48ClN3O10S
Molecular Weight
738.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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