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Mertansine

Product Specifications

CAS Number

139504-50-0

Target

ADC Cytotoxin|||Microtubule Associated

Related Pathways

Cytoskeletal Signaling|||Antibody-drug Conjugate/ADC Related

Purity

>99.99%

Bioactivity

Mertansine is a tubulin inhibitor and an antibody-conjugable maytansinoid alkaloid. The IC50 of Mertansine against HCT-15 and A431 cells is 0.750 and 0.04nM.

Smiles

CO[C@@H]1\C=C/C=C(C)\Cc2cc(OC)c(Cl)c(c2)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCS)[C@@]2(C)O[C@H]2[C@H](C)[C@@H]2C[C@@]1(O)NC(=O)O2

Molecular Formula

C35H48ClN3O10S

Molecular Weight

738.29

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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