CKI-7
Product Specifications
CAS Number
1177141-67-1
Target
ROCK, Casein Kinase, SGK, S6 Kinase, CDK
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Metabolism, Cytoskeletal Signaling, MAPK, Cell Cycle/Checkpoint
Purity
>99.99%
Bioactivity
CKI-7 is a potent, ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor. It also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.
Smiles
Cl.Cl.NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
Molecular Formula
C11H14Cl3N3O2S
Molecular Weight
358.67
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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