Oxatomide
Product Specifications
CAS Number
60607-34-3
Target
P2X Receptor, p38 MAPK, Histamine Receptor, Calcium Channel, 5-HT Receptor, Apoptosis, COX, PERK
Related Pathways
Metabolism, Apoptosis, GPCR/G Protein, Neuroscience, Membrane transporter/Ion channel, Immunology/Inflammation, MAPK
Purity
0.9972
Bioactivity
Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2X7 receptor with an IC50 value of 0.95 μM.Oxatomide has an inhibitory effect on ATP-induced Ca2+ inward currents with an IC50 value of 0.43 μM.Oxatomide inhibits 5-hydroxytryptamine. Oxatomide inhibits 5-hydroxytryptamine with an IC50 of 0.43 μM.Oxatomide is used in the treatment of immune system diseases and in the study of hypersensitivity reactions.
Smiles
O=C1NC2=C(C=CC=C2)N1CCCN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
Molecular Formula
C27H30N4O
Molecular Weight
426.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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