B-Raf IN 11
Product Specifications
CAS Number
918504-27-5
Target
Raf
Related Pathways
MAPK
Purity
0.99947
Bioactivity
B-Raf IN 11 is a novel selective inhibitor. The DFG-in conformation of the B-Raf kinase V600E mutant is superior to the DFG-out conformation in colorectal cancer.
Smiles
C(=O)(C=1C=2C(NC1)=NC=C(Br)C2)C3=C(F)C(NS(CCC)(=O)=O)=CC=C3F
Molecular Formula
C17H14BrF2N3O3S
Molecular Weight
458.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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