Dorsomorphin
Product Specifications
CAS Number
866405-64-3
Target
TGF-beta/Smad, AMPK, Autophagy
Related Pathways
Chromatin/Epigenetic, Stem Cells, Autophagy, PI3K/Akt/mTOR signaling
Purity
0.9948
Bioactivity
Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.
Smiles
C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1
Molecular Formula
C24H25N5O
Molecular Weight
399.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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