Dorsomorphin

Product Specifications

CAS Number

866405-64-3

Target

TGF-beta/Smad, AMPK, Autophagy

Related Pathways

Chromatin/Epigenetic, Stem Cells, Autophagy, PI3K/Akt/mTOR signaling

Purity

0.9948

Bioactivity

Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive. Dorsomorphin inhibits the BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin induces autophagy, and possesses antitumor activity.

Smiles

C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1

Molecular Formula

C24H25N5O

Molecular Weight

399.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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