Infigratinib
Product Specifications
CAS Number
872511-34-7
Target
Apoptosis, FGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis
Purity
0.9897
Bioactivity
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
Smiles
CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1
Molecular Formula
C26H31Cl2N7O3
Molecular Weight
560.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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