Infigratinib

Product Specifications

CAS Number

872511-34-7

Target

Apoptosis|||FGFR

Related Pathways

Tyrosine Kinase/Adaptors|||Angiogenesis|||Apoptosis

Purity

0.9897

Bioactivity

Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.

Smiles

CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1

Molecular Formula

C26H31Cl2N7O3

Molecular Weight

560.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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