Raluridine
Product Specifications
CAS Number
119644-22-3
Target
Others, Nucleoside Antimetabolite/Analog
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Others
Bioactivity
Raluridine is a RNA-directed DNA polymerase inhibitor potentially for the treatment of HIV infection. 935U83 inhibited virus growth with an average 50% inhibitory concentration (IC50: 1.8 microM) corresponding IC50s were 0.10 microM for FLT (3'-deoxy-3'-fluorothymidine) and 0.23, 0.49, and 0.03 microM for the approved agents AZT, ddI (2',3'-dideoxyinosine), and ddC (2',3'-dideoxycytosine), respectively.
Smiles
O=C1N([C@@H]2O[C@H](CO)[C@@H](F)C2)C=C(Cl)C(=O)N1
Molecular Formula
C9H10ClFN2O4
Molecular Weight
264.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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