Zotepine
Product Specifications
CAS Number
26615-21-4
Target
Dopamine Receptor, 5-HT Receptor, Histamine Receptor, Adrenergic Receptor
Related Pathways
Immunology/Inflammation, Neuroscience, GPCR/G Protein
Purity
0.9978
Bioactivity
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. This second-generation antipsychotic is primarily used to treat schizophrenia, and clinical trials have investigated its efficacy as an antimanic agent in patients with acute bipolar mania.
Smiles
CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12
Molecular Formula
C18H18ClNOS
Molecular Weight
331.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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