AZ31
Product Specifications
CAS Number
2088113-98-6
Target
ATM/ATR
Related Pathways
PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Purity
0.981
Bioactivity
AZ31 is an ATM inhibitor with potency, high selectivity, and oral activity.AZ31 inhibits ATM enzymes, intracellular ATM, with IC50 values of <1.2 nM and 46 nM, respectively.AZ31 exhibits excellent ATR selectivity, PIKK family selectivity, and pan-kinase selectivity.AZ31 is a potent in vitro radiosensitizer that can be used for cancer research.
Smiles
N([C@@H](C)C1CCOCC1)C=2C3=C(N=CC2C(N)=O)C=CC(=C3)C=4C=CC(COC)=NC4
Molecular Formula
C24H28N4O3
Molecular Weight
420.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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